Expression and promotor hypermethylation of miR-34a in the various histological subtypes of ovarian cancer

BACKGROUND: An increasing body of evidence shows that miR-34 family has tumor suppressive properties mediating apoptosis, cell cycle arrest and senescence. In ovarian cancer, miR34 family members were found to be under expressed. Particularly miR-34a has been revealed to be a direct transcriptional...

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Vydáno v:BMC Cancer
Hlavní autoři: Schmid, Gabriel, Notaro, Sara, Reimer, Daniel, Abdel-Azim, Samira, Duggan-Peer, Michaela, Holly, Jessica, Fiegl, Heidi, Rössler, Julia, Wiedemair, Annemarie, Concin, Nicole, Altevogt, Peter, Marth, Christian, Zeimet, Alain Gustave
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754861/
https://ncbi.nlm.nih.gov/pubmed/26879132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2135-2
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