Association of Folate Receptor (FOLR1, FOLR2, FOLR3) and Reduced Folate Carrier (SLC19A1) Genes with Meningomyelocele

BACKGROUND: Meningomyelocele (MM) results from lack of closure of the neural tube during embryologic development. Periconceptional folic acid supplementation is a modifier of MM risk in humans, leading to an interest in the folate transport genes as potential candidates for association to MM. METHOD...

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Main Authors: O’Byrne, Michelle R., Au, Kit Sing, Morrison, Alanna C., Lin, Jone-Ing, Fletcher, Jack M., Ostermaier, Kathryn K., Tyerman, Gayle H., Doebel, Sabine, Northrup, Hope
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046546/
https://ncbi.nlm.nih.gov/pubmed/20683905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdra.20706
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