Secreted Isoform of Human Lynx1 (SLURP-2): Spatial Structure and Pharmacology of Interactions with Different Types of Acetylcholine Receptors

Human-secreted Ly-6/uPAR-related protein-2 (SLURP-2) regulates the growth and differentiation of epithelial cells. Previously, the auto/paracrine activity of SLURP-2 was considered to be mediated via its interaction with the α3β2 subtype of the nicotinic acetylcholine receptors (nAChRs). Here, we de...

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Published in:Sci Rep
Main Authors: Lyukmanova, E. N., Shulepko, M. A., Shenkarev, Z. O., Bychkov, M. L., Paramonov, A. S., Chugunov, A. O., Kulbatskii, D. S., Arvaniti, M., Dolejsi, Eva, Schaer, T., Arseniev, A. S., Efremov, R. G., Thomsen, M. S., Dolezal, V., Bertrand, D., Dolgikh, D. A., Kirpichnikov, M. P.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971505/
https://ncbi.nlm.nih.gov/pubmed/27485575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30698
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