Divergent Annexin A1 expression in periphery and gut is associated with systemic immune activation and impaired gut immune response during SIV infection

HIV-1 disease progression is paradoxically characterized by systemic chronic immune activation and gut mucosal immune dysfunction, which is not fully defined. Annexin A1 (ANXA1), an inflammation modulator, is a potential link between systemic inflammation and gut immune dysfunction during the simian...

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Vydáno v:Sci Rep
Hlavní autoři: Sena, Angela A. S., Glavan, Tiffany, Jiang, Guochun, Sankaran-Walters, Sumathi, Grishina, Irina, Dandekar, Satya, Goulart, Luiz R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971494/
https://ncbi.nlm.nih.gov/pubmed/27484833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31157
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