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Targeting p97 to Disrupt Protein Homeostasis in Cancer

Cancer cells are addicted to numerous non-oncogenic traits that enable them to thrive. Proteotoxic stress is one such non-oncogenic trait that is experienced by all tumor cells owing to increased genomic abnormalities and the resulting synthesis and accumulation of non-stoichiometric amounts of cell...

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Bibliografiske detaljer
Udgivet i:Front Oncol
Main Authors: Vekaria, Pratikkumar Harsukhbhai, Home, Trisha, Weir, Scott, Schoenen, Frank J., Rao, Rekha
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971439/
https://ncbi.nlm.nih.gov/pubmed/27536557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2016.00181
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