Gene Coexpression Analyses Differentiate Networks Associated with Diverse Cancers Harboring TP53 Missense or Null Mutations

In a variety of solid cancers, missense mutations in the well-established TP53 tumor suppressor gene may lead to the presence of a partially-functioning protein molecule, whereas mutations affecting the protein encoding reading frame, often referred to as null mutations, result in the absence of p53...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Oros Klein, Kathleen, Oualkacha, Karim, Lafond, Marie-Hélène, Bhatnagar, Sahir, Tonin, Patricia N., Greenwood, Celia M. T.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971393/
https://ncbi.nlm.nih.gov/pubmed/27536319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2016.00137
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