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Cross-talk between 4-1BB and TLR1–TLR2 signaling in CD8(+) T cells regulate TLR2’s costimulatory effects

The activation of TLR-MyD88 (Toll-like receptor- Myeloid differentiation factor 88) signaling within T cells functions as a potent costimulatory signal that boosts antitumor and antiviral responses. However, the molecular mechanisms underlying the costimulatory processes are poorly understood. We co...

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Detalles Bibliográficos
Publicado en:Cancer Immunol Res
Main Authors: Joseph, Ann Mary, Srivastava, Ratika, Zabaleta, Jovanny, Davila, Eduardo
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970957/
https://ncbi.nlm.nih.gov/pubmed/27267778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-15-0173
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