Behavioral deficits and cholinergic pathway abnormalities in male Sanfilippo B mice

Sanfilippo B syndrome is a progressive neurological disorder caused by inability to catabolize heparan sulfate glycosaminoglycans. We studied neurobehavior in male Sanfilippo B mice and heterozygous littermate controls from 16–20 weeks of age. Affected mice showed reduced anxiety, with a decrease in...

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Detaylı Bibliyografya
Yayımlandı:Behav Brain Res
Asıl Yazarlar: Kan, Shih-hsin, Le, Steven Q., Bui, Quang D., Benedict, Braeden, Cushman, Jesse, Sands, Mark S., Dickson, Patricia I.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970944/
https://ncbi.nlm.nih.gov/pubmed/27340089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2016.06.023
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