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Behavioral deficits and cholinergic pathway abnormalities in male Sanfilippo B mice
Sanfilippo B syndrome is a progressive neurological disorder caused by inability to catabolize heparan sulfate glycosaminoglycans. We studied neurobehavior in male Sanfilippo B mice and heterozygous littermate controls from 16–20 weeks of age. Affected mice showed reduced anxiety, with a decrease in...
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| Publicado no: | Behav Brain Res |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4970944/ https://ncbi.nlm.nih.gov/pubmed/27340089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2016.06.023 |
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