Increased Glycogen Synthase Kinase-3β and Hexose-6-Phosphate Dehydrogenase Expression in Adipose Tissue May Contribute to Glucocorticoid-Induced Mouse Visceral Adiposity

BACKGROUND: Increased adiposity in visceral depots is a crucial feature associated with glucocorticoid (GC) excess. The action of GCs in target tissue is regulated by GC receptor (GR) and 11ß-hydroxysteroid dehydrogenase type 1 (11ß-HSD1) coupled with hexose-6-phosphate dehydrogenase (H6pdh). Glycog...

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Publicat a:Int J Obes (Lond)
Autors principals: Yan, Chaoying, Yang, Huabing, Wang, Ying, Dong, Yunzhou, Yu, Fei, Wu, Yong, Wang, Wei, Ume, Adaku, Lutfy, Kabirullah, Friedman, Theodore C., Tian, Shiliu, Liu, Yanjun
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970937/
https://ncbi.nlm.nih.gov/pubmed/27102048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ijo.2016.57
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