Alpha-1 adrenoceptor (ADRA1A) genotype moderates magnitude of acute cocaine-induced subjective effects in cocaine-dependent individuals

OBJECTIVES: We examined whether a functional variant of the ADRA1A gene moderated cocaine-induced subjective effects in a group of cocaine-dependent individuals. METHODS: This study was a within-subject, double blind, placebo-controlled inpatient human laboratory evaluation of 65 non-treatment seeki...

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Bibliographic Details
Published in:Pharmacogenet Genomics
Main Authors: Shorter, Daryl, Nielsen, David A., Hamon, Sara C., Nielsen, Ellen M., Kosten, Thomas R., Newton, Thomas F., De La Garza, Richard
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970930/
https://ncbi.nlm.nih.gov/pubmed/27379509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0000000000000234
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