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Development, validation and application of a comprehensive stereoselective LC/MS–MS assay for bupropion and oxidative, reductive, and glucuronide metabolites in human urine

A stereoselective assay was developed for the quantification of bupropion and oxidative, reductive, and glucuronide metabolites (16 analytes total) in human urine. Initially, authentic glucuronide standards obtained from commercial sources were found to be incorrectly labeled with regard to stereoch...

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Pubblicato in:J Chromatogr B Analyt Technol Biomed Life Sci
Autori principali: Teitelbaum, Aaron M., Flaker, Alicia M., Kharasch, Evan D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970645/
https://ncbi.nlm.nih.gov/pubmed/27318149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2016.05.036
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