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Dual inhibition of Mcl-1 by the combination of carfilzomib and TG02 in multiple myeloma
Carfilzomib (Kyprolis®), a second generation proteasome inhibitor, is FDA approved for single-agent use among relapsed/refractory multiple myeloma (MM). To enhance the therapeutic efficacy of carfilzomib, we sought to combine carfilzomib with other novel agents. TG02, a multi-kinase inhibitor, targe...
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| Publicat a: | Cancer Biol Ther |
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| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4970534/ https://ncbi.nlm.nih.gov/pubmed/27246906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2016.1192086 |
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