Conformational heterogeneity in closed and open states of the KcsA potassium channel in lipid bicelles

The process of ion channel gating—opening and closing—involves local and global structural changes in the channel in response to external stimuli. Conformational changes depend on the energetic landscape that underlies the transition between closed and open states, which plays a key role in ion chan...

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Bibliographic Details
Published in:J Gen Physiol
Main Authors: Kim, Dorothy M., Dikiy, Igor, Upadhyay, Vikrant, Posson, David J., Eliezer, David, Nimigean, Crina M.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2016
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4969796/
https://ncbi.nlm.nih.gov/pubmed/27432996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201611602
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