Low prevalence of dihydro folate reductase (dhfr) and dihydropteroate synthase (dhps) quadruple and quintuple mutant alleles associated with SP resistance in Plasmodium vivax isolates of West Bengal, India

BACKGROUND: Emergence of chloroquine resistant Plasmodium vivax is a serious obstacle towards malaria control in India. This study elucidates the temporal pattern of antifolate [sulfadoxine–pyrimethamine (SP)] resistance in P. vivax infection by means of genetic polymorphisms, especially analysing t...

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Detalles Bibliográficos
Publicado en:Malar J
Autores principales: Das, Sabyasachi, Banik, Abhijit, Hati, Amiya Kumar, Roy, Somenath
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4969723/
https://ncbi.nlm.nih.gov/pubmed/27485211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-016-1445-9
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