Genetic mutations in Plasmodium falciparum and Plasmodium vivax dihydrofolate reductase (DHFR) and dihydropteroate synthase (DHPS) in Vanuatu and Solomon Islands prior to the introduction of artemisinin combination therapy

BACKGROUND: Plasmodium falciparum and Plasmodium vivax are endemic in Vanuatu and the Solomon Islands. While both countries have introduced artemether-lumefantrine (AL) as first-line therapy for both P. falciparum and P. vivax since 2008, chloroquine and sulphadoxine-pyrimethamine (SP) were used as...

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Bibliografiska uppgifter
Huvudupphovsmän: Gresty, Karryn J, Gray, Karen-Ann, Bobogare, Albino, Wini, Lyndes, Taleo, George, Hii, Jeffrey, Cheng, Qin, Waters, Norman C
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2014
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4203929/
https://ncbi.nlm.nih.gov/pubmed/25311473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-13-402
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