Declining trend of Plasmodium falciparum dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) mutant alleles after the withdrawal of Sulfadoxine-Pyrimethamine in North Western Ethiopia

Antimalarial drug resistance is one of the major challenges in global efforts of malaria control and elimination. In 1998, chloroquine was abandoned and replaced with sulfadoxine/pyrimethamine, which in turn was replaced with artemether/lumefantrine for the treatment of uncomplicated falciparum mala...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Tessema, Sofonias K., Kassa, Moges, Kebede, Amha, Mohammed, Hussein, Leta, Gemechu Tadesse, Woyessa, Adugna, Guma, Geremew Tasew, Petros, Beyene
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591967/
https://ncbi.nlm.nih.gov/pubmed/26431464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126943
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