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Dihydropyridine Derivatives Modulate Heat Shock Responses and have a Neuroprotective Effect in a Transgenic Mouse Model of Alzheimer’s Disease

Heat shock proteins (Hsps) have chaperone activity and play a pivotal role in the homeostasis of proteins by preventing misfolding, by clearing aggregated and damaged proteins from cells, and by maintaining proteins in an active state. Alzheimer’s disease (AD) is thought to be caused by amyloid-β pe...

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書誌詳細
出版年:J Alzheimers Dis
主要な著者: Kasza, Ágnes, Hunya, Ákos, Frank, Zsuzsa, Fülöp, Ferenc, Török, Zsolt, Balogh, Gábor, Sántha, Miklós, Bálind, Árpád, Bernáth, Sándor, Blundell, Katie L.I.M., Prodromou, Chrisostomos, Horváth, Ibolya, Zeiler, Hans-Joachim, Hooper, Philip L., Vigh, László, Penke, Botond
フォーマット: Artigo
言語:Inglês
出版事項: IOS Press 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4969717/
https://ncbi.nlm.nih.gov/pubmed/27163800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-150860
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