Dihydropyridine Derivatives Modulate Heat Shock Responses and have a Neuroprotective Effect in a Transgenic Mouse Model of Alzheimer’s Disease

Heat shock proteins (Hsps) have chaperone activity and play a pivotal role in the homeostasis of proteins by preventing misfolding, by clearing aggregated and damaged proteins from cells, and by maintaining proteins in an active state. Alzheimer’s disease (AD) is thought to be caused by amyloid-β pe...

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Veröffentlicht in:J Alzheimers Dis
Hauptverfasser: Kasza, Ágnes, Hunya, Ákos, Frank, Zsuzsa, Fülöp, Ferenc, Török, Zsolt, Balogh, Gábor, Sántha, Miklós, Bálind, Árpád, Bernáth, Sándor, Blundell, Katie L.I.M., Prodromou, Chrisostomos, Horváth, Ibolya, Zeiler, Hans-Joachim, Hooper, Philip L., Vigh, László, Penke, Botond
Format: Artigo
Sprache:Inglês
Veröffentlicht: IOS Press 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4969717/
https://ncbi.nlm.nih.gov/pubmed/27163800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-150860
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