Dihydropyridine Derivatives Modulate Heat Shock Responses and have a Neuroprotective Effect in a Transgenic Mouse Model of Alzheimer’s Disease

Heat shock proteins (Hsps) have chaperone activity and play a pivotal role in the homeostasis of proteins by preventing misfolding, by clearing aggregated and damaged proteins from cells, and by maintaining proteins in an active state. Alzheimer’s disease (AD) is thought to be caused by amyloid-β pe...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Kasza, Ágnes, Hunya, Ákos, Frank, Zsuzsa, Fülöp, Ferenc, Török, Zsolt, Balogh, Gábor, Sántha, Miklós, Bálind, Árpád, Bernáth, Sándor, Blundell, Katie L.I.M., Prodromou, Chrisostomos, Horváth, Ibolya, Zeiler, Hans-Joachim, Hooper, Philip L., Vigh, László, Penke, Botond
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4969717/
https://ncbi.nlm.nih.gov/pubmed/27163800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-150860
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