SRT1720, a SIRT1 specific activator, protected H(2)O(2)-induced senescent endothelium

Silent information regulator 1 (SIRT1) plays a critical role in maintaining vascular homeostasis via modulating senescent-related signal pathway, however, the molecular mechanism remains modest clarified. The purpose of this study was to examine whether SIRT1 specific activator SRT1720 would exhibit...

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Vydáno v:Am J Transl Res
Hlavní autoři: Li, Rui-Lin, Lu, Zhao-Yang, Huang, Jing-Juan, Qi, Jia, Hu, An, Su, Zhi-Xiao, Zhang, Lan, Li, Yue, Shi, Yi-Qin, Hao, Chang-Ning, Duan, Jun-Li
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2016
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4969425/
https://ncbi.nlm.nih.gov/pubmed/27508009
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