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Preclinical models for interrogating drug action in human cancers using Stable Isotope Resolved Metabolomics (SIRM)

AIMS: In this review we compare the advantages and disadvantages of different model biological systems for determining the metabolic functions of cells in complex environments, how they may change in different disease states, and respond to therapeutic interventions. BACKGROUND: All preclinical drug...

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Dettagli Bibliografici
Pubblicato in:Metabolomics
Autori principali: Lane, Andrew N., Higashi, Richard M., Fan, Teresa W-M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968890/
https://ncbi.nlm.nih.gov/pubmed/27489532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11306-016-1065-y
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