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Preclinical models for interrogating drug action in human cancers using Stable Isotope Resolved Metabolomics (SIRM)

AIMS: In this review we compare the advantages and disadvantages of different model biological systems for determining the metabolic functions of cells in complex environments, how they may change in different disease states, and respond to therapeutic interventions. BACKGROUND: All preclinical drug...

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Detaylı Bibliyografya
Yayımlandı:Metabolomics
Asıl Yazarlar: Lane, Andrew N., Higashi, Richard M., Fan, Teresa W-M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968890/
https://ncbi.nlm.nih.gov/pubmed/27489532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11306-016-1065-y
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