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Preclinical models for interrogating drug action in human cancers using Stable Isotope Resolved Metabolomics (SIRM)

AIMS: In this review we compare the advantages and disadvantages of different model biological systems for determining the metabolic functions of cells in complex environments, how they may change in different disease states, and respond to therapeutic interventions. BACKGROUND: All preclinical drug...

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Detalhes bibliográficos
Publicado no:Metabolomics
Main Authors: Lane, Andrew N., Higashi, Richard M., Fan, Teresa W-M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968890/
https://ncbi.nlm.nih.gov/pubmed/27489532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11306-016-1065-y
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