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Preclinical models for interrogating drug action in human cancers using Stable Isotope Resolved Metabolomics (SIRM)

AIMS: In this review we compare the advantages and disadvantages of different model biological systems for determining the metabolic functions of cells in complex environments, how they may change in different disease states, and respond to therapeutic interventions. BACKGROUND: All preclinical drug...

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Detalles Bibliográficos
Publicado en:Metabolomics
Main Authors: Lane, Andrew N., Higashi, Richard M., Fan, Teresa W-M.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968890/
https://ncbi.nlm.nih.gov/pubmed/27489532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11306-016-1065-y
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