Danazol Treatment for Telomere Diseases

BACKGROUND: Genetic defects in telomere maintenance and repair cause bone marrow failure, liver cirrhosis, and pulmonary fibrosis, and they increase susceptibility to cancer. Historically, androgens have been useful as treatment for marrow failure syndromes. In tissue culture and animal models, sex...

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Bibliografiske detaljer
Udgivet i:N Engl J Med
Main Authors: Townsley, Danielle M., Dumitriu, Bogdan, Liu, Delong, Biancotto, Angélique, Weinstein, Barbara, Chen, Christina, Hardy, Nathan, Mihalek, Andrew D., Lingala, Shilpa, Kim, Yun Ju, Yao, Jianhua, Jones, Elizabeth, Gochuico, Bernadette R., Heller, Theo, Wu, Colin O., Calado, Rodrigo T., Scheinberg, Phillip, Young, Neal S.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968696/
https://ncbi.nlm.nih.gov/pubmed/27192671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1515319
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