Telomere Content Measurement in Human Hematopoietic Cells: Comparative Analysis of qPCR and Flow-FISH Techniques

Abnormal telomere lengths have been linked to cancer and other hematologic disorders. Determination of mean telomere content (MTC) is traditionally performed by Southern blotting and densitometry, giving a mean telomere restriction fragment (TRF) value for the total cell population studied. Here, we...

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Detalhes bibliográficos
Publicado no:Cytometry A
Main Authors: Wand, Taylor, Fang, Mike, Chen, Christina, Hardy, Nathan, McCoy, J. Philip, Dumitriu, Bogdan, Young, Neal S., Biancotto, Angélique
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482817/
https://ncbi.nlm.nih.gov/pubmed/27717244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cyto.a.22982
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