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A hingeless Fc fusion system for site-specific cleavage by IdeS

Fusion of proteins to the Fc region of IgG is widely used to express cellular receptors and other extracellular proteins, but cleavage of the fusion partner is sometimes required for downstream applications. Immunoglobulin G-degrading enzyme of Streptococcus pyogenes (IdeS) is a protease with exquis...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Novarra, Shabazz, Grinberg, Luba, Rickert, Keith W., Barnes, Arnita, Wilson, Susan, Baca, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968090/
https://ncbi.nlm.nih.gov/pubmed/27210548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2016.1186321
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