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A hingeless Fc fusion system for site-specific cleavage by IdeS
Fusion of proteins to the Fc region of IgG is widely used to express cellular receptors and other extracellular proteins, but cleavage of the fusion partner is sometimes required for downstream applications. Immunoglobulin G-degrading enzyme of Streptococcus pyogenes (IdeS) is a protease with exquis...
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| Udgivet i: | MAbs |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4968090/ https://ncbi.nlm.nih.gov/pubmed/27210548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2016.1186321 |
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