Inhibition of DNA methylation promotes breast tumor sensitivity to netrin‐1 interference

In a number of human cancers, NTN1 upregulation inhibits apoptosis induced by its so‐called dependence receptors DCC and UNC5H, thus promoting tumor progression. In other cancers however, the selective inhibition of this dependence receptor death pathway relies on the silencing of pro‐apoptotic effe...

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Dettagli Bibliografici
Pubblicato in:EMBO Mol Med
Autori principali: Grandin, Mélodie, Mathot, Pauline, Devailly, Guillaume, Bidet, Yannick, Ghantous, Akram, Favrot, Clementine, Gibert, Benjamin, Gadot, Nicolas, Puisieux, Isabelle, Herceg, Zdenko, Delcros, Jean‐Guy, Bernet, Agnès, Mehlen, Patrick, Dante, Robert
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967941/
https://ncbi.nlm.nih.gov/pubmed/27378792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201505945
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