טוען...
Combining chemotherapeutic agents and netrin-1 interference potentiates cancer cell death
The secreted factor netrin-1 is upregulated in a fraction of human cancers as a mechanism to block apoptosis induced by netrin-1 dependence receptors DCC and UNC5H. Targeted therapies aiming to trigger tumour cell death via netrin-1/receptors interaction interference are under preclinical evaluation...
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| Main Authors: | , , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
John Wiley and Sons
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3914534/ https://ncbi.nlm.nih.gov/pubmed/24293316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201302654 |
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