Inhibition of DNA methylation promotes breast tumor sensitivity to netrin‐1 interference

In a number of human cancers, NTN1 upregulation inhibits apoptosis induced by its so‐called dependence receptors DCC and UNC5H, thus promoting tumor progression. In other cancers however, the selective inhibition of this dependence receptor death pathway relies on the silencing of pro‐apoptotic effe...

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Bibliografiske detaljer
Udgivet i:EMBO Mol Med
Main Authors: Grandin, Mélodie, Mathot, Pauline, Devailly, Guillaume, Bidet, Yannick, Ghantous, Akram, Favrot, Clementine, Gibert, Benjamin, Gadot, Nicolas, Puisieux, Isabelle, Herceg, Zdenko, Delcros, Jean‐Guy, Bernet, Agnès, Mehlen, Patrick, Dante, Robert
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967941/
https://ncbi.nlm.nih.gov/pubmed/27378792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201505945
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