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HCV derived from sera of HCV-infected patients induces pro-fibrotic effects in human primary fibroblasts by activating GLI2

Hepatitis C virus (HCV) infection is a leading cause of liver fibrosis, especially in developing countries. The process is characterized by the excess accumulation of ECM that may lead, over time, to hepatic cirrhosis, liver failure and also to hepatocarcinoma. The direct role of HCV in promoting fi...

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Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Granato, M., Zompetta, C., Vescarelli, E., Rizzello, C., Cardi, A., Valia, S., Antonelli, G., Marchese, C., Torrisi, M. R., Faggioni, A., Cirone, M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967919/
https://ncbi.nlm.nih.gov/pubmed/27476557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30649
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