Adventitial Fibroblasts induce a distinct Pro-inflammatory/Pro-fibrotic Macrophage Phenotype in Pulmonary Hypertension

Macrophage accumulation is not only a characteristic hallmark but also a critical component of pulmonary artery (PA) remodeling associated with pulmonary hypertension (PH). However, the cellular and molecular mechanisms that drive vascular macrophage activation and their functional phenotype remain...

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Bibliografiske detaljer
Main Authors: El Kasmi, Karim C., Pugliese, Steven C., Riddle, Suzette R., Poth, Jens M., Anderson, Aimee L., Frid, Maria G., Li, Min, Pullamsetti, Soni S., Savai, Rajkumar, Nagel, Maria A., Fini, Mehdi A., Graham, Brian B., Tuder, Rubin M., Friedman, Jacob E., Eltzschig, Holger K., Sokol, Ronald J., Stenmark, Kurt R.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100597/
https://ncbi.nlm.nih.gov/pubmed/24928992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303048
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