Adventitial Fibroblasts induce a distinct Pro-inflammatory/Pro-fibrotic Macrophage Phenotype in Pulmonary Hypertension

Macrophage accumulation is not only a characteristic hallmark but also a critical component of pulmonary artery (PA) remodeling associated with pulmonary hypertension (PH). However, the cellular and molecular mechanisms that drive vascular macrophage activation and their functional phenotype remain...

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Autores principales: El Kasmi, Karim C., Pugliese, Steven C., Riddle, Suzette R., Poth, Jens M., Anderson, Aimee L., Frid, Maria G., Li, Min, Pullamsetti, Soni S., Savai, Rajkumar, Nagel, Maria A., Fini, Mehdi A., Graham, Brian B., Tuder, Rubin M., Friedman, Jacob E., Eltzschig, Holger K., Sokol, Ronald J., Stenmark, Kurt R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100597/
https://ncbi.nlm.nih.gov/pubmed/24928992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303048
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