Adventitial Fibroblasts induce a distinct Pro-inflammatory/Pro-fibrotic Macrophage Phenotype in Pulmonary Hypertension

Macrophage accumulation is not only a characteristic hallmark but also a critical component of pulmonary artery (PA) remodeling associated with pulmonary hypertension (PH). However, the cellular and molecular mechanisms that drive vascular macrophage activation and their functional phenotype remain...

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Autori principali: El Kasmi, Karim C., Pugliese, Steven C., Riddle, Suzette R., Poth, Jens M., Anderson, Aimee L., Frid, Maria G., Li, Min, Pullamsetti, Soni S., Savai, Rajkumar, Nagel, Maria A., Fini, Mehdi A., Graham, Brian B., Tuder, Rubin M., Friedman, Jacob E., Eltzschig, Holger K., Sokol, Ronald J., Stenmark, Kurt R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100597/
https://ncbi.nlm.nih.gov/pubmed/24928992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303048
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