Mature dendritic cells cause Th17/Treg imbalance by secreting TGF-β1 and IL-6 in the pathogenesis of experimental autoimmune encephalomyelitis

Multiple sclerosis (MS) is generally acknowledged to be an autoimmune disease, but its etiology remains unknown. The most intensively studied animal model of MS is experimental autoimmune encephalomyelitis (EAE). Dendritic cells (DCs), the professional antigen presenting cells (APCs), have gained in...

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Vydáno v:Cent Eur J Immunol
Hlavní autoři: Lu, Pingxia, Cao, Yingping, Wang, Meihua, Zheng, Peizheng, Hou, Juan, Zhu, Chanhong, Hu, Jianda
Médium: Artigo
Jazyk:Inglês
Vydáno: Polish Society of Experimental and Clinical Immunology 2016
Témata:
Experimental Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967648/
https://ncbi.nlm.nih.gov/pubmed/27536199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/ceji.2016.60987
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