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The Interplay of Permanent Charge and Hydrophobicity in the Electrospray Ionization of Glycans
The analysis of N-linked glycans by mass spectrometry (MS) has been characterized by low signal-to-noise ratios and high limits of detection due to their hydrophilicity and lack of basic sites able to be protonated. As a result, every step in glycan sample preparation must be thoroughly optimized in...
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| Gepubliceerd in: | Anal Chem |
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| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2010
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4967534/ https://ncbi.nlm.nih.gov/pubmed/20590124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac101227a |
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