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Stable-Isotope Labeled Hydrophobic Hydrazide Reagents for the Relative Quantification of N-linked Glycans by Electrospray Ionization Mass Spectrometry

This study presents the development of stable-isotope labeled hydrophobic, hydrazide reagents for the relative quantification of N-linked glycans. The P2GPN ‘light’ ((12)C) and ‘heavy’ ((13)C(6)) pair are used to differentially label two N-linked glycan samples. The samples are combined 1:1, separat...

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Autori principali: Walker, S. Hunter, Budhathoki-Uprety, Januka, Novak, Bruce M., Muddiman, David C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184603/
https://ncbi.nlm.nih.gov/pubmed/21774516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac201376q
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