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Modifying the Charge State Distribution of Proteins in Electrospray Ionization Mass Spectrometry by Chemical Derivatization

Electrospray ionization (ESI) of denatured proteins produces a broad distribution of multiply-charged ions leading to multiple peaks in the mass spectrum. We investigated changes in the positive-mode ESI charge state distribution produced by several chemical modifications of denatured proteins. Capp...

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Bibliografski detalji
Glavni autori: Krusemark, Casey J., Frey, Brian L., Belshaw, Peter J., Smith, Lloyd M.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776692/
https://ncbi.nlm.nih.gov/pubmed/19481956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jasms.2009.04.017
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