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Controlling Gas-Phase Reactions for Efficient Charge Reduction Electrospray Mass Spectrometry of Intact Proteins

Charge reduction electrospray mass spectrometry (CREMS) reduces the charge states of electrospray-generated ions, which concentrates the ions from a protein into fewer peaks spread over a larger m/z range, thereby increasing peak separation and decreasing spectral congestion. An optimized design for...

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Detalhes bibliográficos
Main Authors: Frey, Brian L., Lin, Yuan, Westphall, Michael S., Smith, Lloyd M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489883/
https://ncbi.nlm.nih.gov/pubmed/16198118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jasms.2005.07.019
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