Runx1 Regulates Myeloid Precursor Differentiation Into Osteoclasts Without Affecting Differentiation Into Antigen Presenting or Phagocytic Cells in Both Males and Females

Runt-related transcription factor 1 (Runx1), a master regulator of hematopoiesis, is expressed in preosteoclasts. Previously we evaluated the bone phenotype of CD11b-Cre Runx1(fl/fl) mice and demonstrated enhanced osteoclasts and decreased bone mass in males. However, an assessment of the effects of...

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Bibliographische Detailangaben
Veröffentlicht in:Endocrinology
Hauptverfasser: Paglia, David N., Yang, Xiaochuan, Kalinowski, Judith, Jastrzebski, Sandra, Drissi, Hicham, Lorenzo, Joseph
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2016
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967120/
https://ncbi.nlm.nih.gov/pubmed/27267711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-2037
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