A Mixed Micelle Formulation for Oral Delivery of Vitamin K

PURPOSE: To develop a stable micellar formulation of vitamin K for oral delivery, because the commercial and clinically used formulation of vitamin K (Konakion® MM) destabilizes at gastric pH resulting in low bioavailability of this vitamin in neonates with cholestasis. METHODS: Mixed micelles compo...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Pharm Res
Main Authors: Sun, Feilong, Jaspers, Tessa C. C., van Hasselt, Peter M., Hennink, Wim E., van Nostrum, Cornelus F.
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2016
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967097/
https://ncbi.nlm.nih.gov/pubmed/27245464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-016-1954-9
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