Influence of PEGylation of Vitamin-K-Loaded Mixed Micelles on the Uptake by and Transport through Caco-2 Cells

[Image: see text] The aim of the study is to investigate the uptake by and transport through Caco-2 cells of two mixed micelle formulations (based on egg phosphatidylcholine and glycocholic acid) of vitamin K, i.e., with and without DSPE-PEG2000. The uptake of vitamin K and fluorescently labeled mix...

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Bibliografiske detaljer
Udgivet i:Mol Pharm
Main Authors: Sun, Feilong, Adrian, Max, Beztsinna, Nataliia, van den Dikkenberg, Joep B., Maas-Bakker, Roel F., van Hasselt, Peter M., van Steenbergen, Mies J., Su, Xiangjie, Kapitein, Lukas C., Hennink, Wim E., van Nostrum, Cornelus F.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2018
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6150738/
https://ncbi.nlm.nih.gov/pubmed/30063364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.8b00258
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