Φορτώνει......
Hyperactivation of ATM upon DNA-PKcs inhibition modulates p53 dynamics and cell fate in response to DNA damage
A functional DNA damage response is essential for maintaining genome integrity in the presence of DNA double-strand breaks. It is mainly coordinated by the kinases ATM, ATR, and DNA-PKcs, which control the repair of broken DNA strands and relay the damage signal to the tumor suppressor p53 to induce...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Mol Biol Cell |
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| Κύριοι συγγραφείς: | , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
The American Society for Cell Biology
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4966978/ https://ncbi.nlm.nih.gov/pubmed/27280387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-01-0032 |
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