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The genetic variants in 3’ untranslated region of voltage-gated sodium channel alpha 1 subunit gene affect the mRNA-microRNA interactions and associate with epilepsy

BACKGROUND: mRNA expression in a cell or subcellular organelle is precisely regulated for the purpose of gene function regulation. The 3’ untranslated region (3’UTR) of mRNA is the binding target of microRNA and RNA binding proteins. Their interactions regulate mRNA level in specific subcellular reg...

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Detaylı Bibliyografya
Yayımlandı:BMC Genet
Asıl Yazarlar: Li, Tian, Kuang, Yaoyun, Li, Bin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966731/
https://ncbi.nlm.nih.gov/pubmed/27473590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-016-0417-y
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