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The genetic variants in 3’ untranslated region of voltage-gated sodium channel alpha 1 subunit gene affect the mRNA-microRNA interactions and associate with epilepsy

BACKGROUND: mRNA expression in a cell or subcellular organelle is precisely regulated for the purpose of gene function regulation. The 3’ untranslated region (3’UTR) of mRNA is the binding target of microRNA and RNA binding proteins. Their interactions regulate mRNA level in specific subcellular reg...

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Detalhes bibliográficos
Publicado no:BMC Genet
Main Authors: Li, Tian, Kuang, Yaoyun, Li, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966731/
https://ncbi.nlm.nih.gov/pubmed/27473590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-016-0417-y
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