Calpain Mediates Proteolysis of the Voltage-Gated Sodium Channel α-Subunit

Alterations in the expression, molecular composition, and localization of voltage-gated sodium channels play major roles in a broad range of neurological disorders. Recent evidence identifies sodium channel proteolysis as a key early event after ischemia and traumatic brain injury, further expanding...

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Bibliographic Details
Main Authors: von Reyn, Catherine R., Spaethling, Jennifer M., Mesfin, Mahlet N., Ma, Marek, Neumar, Robert W., Smith, Douglas H., Siman, Robert, Meaney, David F.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2009
Subjects:
Brief Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799681/
https://ncbi.nlm.nih.gov/pubmed/19692609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2339-09.2009
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