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The genetic variants in 3’ untranslated region of voltage-gated sodium channel alpha 1 subunit gene affect the mRNA-microRNA interactions and associate with epilepsy

BACKGROUND: mRNA expression in a cell or subcellular organelle is precisely regulated for the purpose of gene function regulation. The 3’ untranslated region (3’UTR) of mRNA is the binding target of microRNA and RNA binding proteins. Their interactions regulate mRNA level in specific subcellular reg...

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Vydáno v:BMC Genet
Hlavní autoři: Li, Tian, Kuang, Yaoyun, Li, Bin
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966731/
https://ncbi.nlm.nih.gov/pubmed/27473590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-016-0417-y
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