A comparison of the ability of the human IgG1 allotypes G1m3 and G1m1,17 to stimulate T-cell responses from allotype matched and mismatched donors

The immunogenicity of clinically administered antibodies has clinical implications for the patients receiving them, ranging from mild consequences, such as increased clearance of the drug from the circulation, to life-threatening effects. The emergence of methods to engineer variable regions resulti...

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Publicado en:MAbs
Main Authors: Webster, Carl I., Bryson, Christine J., Cloake, Edward A., Jones, Tim D., Austin, Mark J., Karle, Anette C., Spindeldreher, Sebastian, Lowe, David C., Baker, Matthew P.
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966604/
https://ncbi.nlm.nih.gov/pubmed/26821574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1128605
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