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Endothelial Nitric Oxide Synthase (−786T>C) and Endothelin-1 (5665G>T) Gene Polymorphisms as Vascular Dysfunction Risk Factors in Sickle Cell Anemia

Sickle cell anemia (SCA) patients have vascular complications, and polymorphisms in endothelin-1 (ET-1) and endothelial nitric oxide synthase (eNOS) genes were associated with ET-1 and nitric oxide disturbance. We investigate the association of ET-1 5665G>T and eNOS −786T>C polymorphisms with...

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Библиографические подробности
Опубликовано в: :Gene Regul Syst Bio
Главные авторы: Vilas-Boas, Wendell, Figueiredo, Camylla V. B., Pitanga, Thassila N., Carvalho, Magda O. S., Santiago, Rayra P., Santana, Sânzio S., Guarda, Caroline C., Zanette, Angela M. D., Cerqueira, Bruno A. V., Gonçalves, Marilda S.
Формат: Artigo
Язык:Inglês
Опубликовано: Libertas Academica 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966487/
https://ncbi.nlm.nih.gov/pubmed/27486304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/GRSB.S38276
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