Endothelial Nitric Oxide Synthase (−786T>C) and Endothelin-1 (5665G>T) Gene Polymorphisms as Vascular Dysfunction Risk Factors in Sickle Cell Anemia

Sickle cell anemia (SCA) patients have vascular complications, and polymorphisms in endothelin-1 (ET-1) and endothelial nitric oxide synthase (eNOS) genes were associated with ET-1 and nitric oxide disturbance. We investigate the association of ET-1 5665G>T and eNOS −786T>C polymorphisms with...

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Detalhes bibliográficos
Publicado no:Gene Regul Syst Bio
Main Authors: Vilas-Boas, Wendell, Figueiredo, Camylla V. B., Pitanga, Thassila N., Carvalho, Magda O. S., Santiago, Rayra P., Santana, Sânzio S., Guarda, Caroline C., Zanette, Angela M. D., Cerqueira, Bruno A. V., Gonçalves, Marilda S.
Formato: Artigo
Idioma:Inglês
Publicado em: Libertas Academica 2016
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966487/
https://ncbi.nlm.nih.gov/pubmed/27486304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/GRSB.S38276
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